Ozone is a highly reactive gas that is formed naturally in the atmosphere and plays a critical role in protecting the Earth from harmful ultraviolet radiation. However, ozone can also be produced by human activities and can have negative impacts on human health and the environment.

In the context of commerce, ozone is often associated with the ozone layer, which is a thin layer of ozone in the Earth's stratosphere that protects the planet from harmful UV radiation. The depletion of the ozone layer, primarily due to the release of chlorofluorocarbons (CFCs) and other ozone-depleting substances (ODS), led to the development of the Montreal Protocol, an international treaty designed to phase out the production and consumption of ODS.

The commerce of ozone-depleting substances was once a significant industry, with these substances used in a variety of applications, including refrigeration, air conditioning, and industrial processes. However, the phase-out of ODS under the Montreal Protocol has led to a decline in the use of these substances, with many countries transitioning to alternatives that are less harmful to the ozone layer.

In addition to ODS, ozone can also be produced as a byproduct of other human activities, such as combustion processes and certain types of industrial production. In high concentrations, ozone can have negative impacts on human health, causing respiratory problems and other health issues.

Despite the negative impacts of ozone on human health and the environment, ozone is also used in certain commercial applications. For example, ozone can be used as a disinfectant, helping to remove harmful bacteria and viruses from water and air. Ozone can also be used to treat certain medical conditions, such as chronic wounds and skin disorders.

Overall, the commerce of ozone is complex, with both positive and negative impacts on human health and the environment. While the phase-out of ozone-depleting substances under the Montreal Protocol has been successful in protecting the ozone layer, the continued production and use of ozone in certain applications highlights the need for careful consideration of the potential impacts of this highly reactive gas.